A 21-day Rockies, Southern California and Route 66 loop from northern Illinois
Estimated cost
Estimates generated at planning time — your actual costs may vary.
Day-by-day itinerary
Herbert Hoover National Historic Site
Presidential birthplace and historic village
Pullman Bar & Diner
Popular diner serving seasonal American fare
University of Iowa Museum of Natural History
Iowa geology, wildlife and cultural exhibits
Hickory Hill Park
Woodland trails and spring wildflowers
the Webster
Acclaimed Midwestern cooking in a historic hall
Graduate by Hilton Iowa City
Central hotel with covered parking nearby
Neal Smith National Wildlife Refuge
Restored tallgrass prairie with bison and elk
Goldie's Ice Cream Shoppe
Award-winning Iowa tenderloins and sandwiches
Bob Kerrey Pedestrian Bridge
Missouri River bridge and skyline viewpoint
The Durham Museum
Regional history inside an Art Deco station
Block 16
Creative farm-to-table street food
Cambria Hotel Omaha Downtown
Modern downtown hotel with convenient parking
Omaha's Henry Doorly Zoo and Aquarium
Major zoo with indoor rainforest and desert
Railcar Modern American Kitchen
Seasonal American lunch with regional ingredients
Strategic Air Command & Aerospace Museum
Cold War aircraft and space-history collection
Alley Rose
Long-running downtown steak and seafood restaurant
Crowne Plaza Kearney by IHG
Comfortable interstate hotel with ample parking
Golden Spike Tower
Panoramic view over the world’s largest rail yard
Pals Brewing Company
Nebraska brewpub with pizzas and salads
Fort Cody Trading Post
Quirky roadside museum and miniature Wild West show
Pawnee National Grasslands Birding Tour
Open prairie habitat for raptors and grassland birds
Bluebird Cafe
Red Rocks Park and Amphitheatre
Sandstone formations and landmark amphitheatre
The Fort
Historic adobe restaurant serving regional game
History Colorado Center
Interactive museum covering Colorado history
Denver Botanic Gardens
Landscaped gardens with spring color
Potager
Seasonal neighborhood restaurant with local produce
Hyatt Place Denver/Downtown
Central hotel near museums and Civic Center
Denver Art Museum
Western American, Indigenous and global art
Leven Deli Co.
Highly regarded deli near the museum district
Colorado State Capitol
Historic capitol with mountain-view steps
Clear Creek Trail
Creekside walking path beneath foothills
Abejas Golden
Seasonal New American dining in historic Golden
The Golden Hotel, an Ascend Collection Hotel
Creekside hotel with convenient parking
Georgetown Loop Railroad
Historic narrow-gauge railway in Clear Creek Canyon
Cooper's on the Creek
Mountain lunch beside Clear Creek
Frisco Historic Park and Museum
Free local-history museum and preserved cabins
Sapphire Point Overlook
Short trail overlooking Dillon Reservoir
Glenwood Hot Springs Pool
Historic mineral pools beneath canyon walls
The Pullman
Creative Colorado comfort food downtown
Hotel Colorado
Landmark historic hotel opposite the hot springs
Colorado National Monument Sign
Canyon overlooks and desert hiking trails
Hot Tomato Pizza
Popular cyclist-friendly pizzeria
Dinosaur Journey Museum
Fossils and regional paleontology exhibits
Dead Horse Point State Park
High overlook above the Colorado River
Desert Bistro
Refined Southwestern dinner in Moab
Hyatt Place Moab
Modern hotel with pool and open parking
98 Center Moab
Fresh Vietnamese-inspired sandwiches and bowls
Red Fort Cuisine of India
Best Western Plus Abbey Inn
Reliable mid-range hotel with large parking lot
Snow Canyon State Park
Lava flows, red cliffs and short desert trails
Xetava
Southwestern café overlooking red cliffs
Tuacahn Center for the Arts
Red-rock amphitheatre and cultural venue
St. George Dinosaur Discovery Site at Johnson Farm
In-place dinosaur tracks and fossils
Red Hills Desert Garden
Free desert garden with red-rock views
Wood Ash Rye
Regional small plates and wood-fired cooking
Inn on The Cliff St. George
Clifftop hotel with broad valley views
Valley of Fire State Park
Red sandstone formations and petroglyphs
The Inside Scoop
Casual local café serving sandwiches and shakes
The Neon Museum Las Vegas
Historic casino signs and design archive
The Mob Museum
Organized-crime and law-enforcement history
Carson Kitchen
Inventive downtown small plates
Park MGM Las Vegas
Smoke-free Strip resort with structured parking
Seven Magic Mountains
Colorful desert art installation
Kelso Depot Visitor Center
Restored desert railway depot and exhibits
Emma Jean's Holland Burger Cafe
Historic Route 66 roadside diner
Mission San Juan Capistrano
Historic mission, gardens and preserved ruins
Heritage Barbecue
Acclaimed live-fire California barbecue
Ayres Hotel & Spa Mission Viejo - Lake Forest
Comfortable spa hotel with open parking
O'Neill Regional Park
Oak woodland trails and bird habitat
Rancho Santa Margarita Lake
Easy lakeside walk with mountain views
Hanna's
Popular local restaurant with California cuisine
Richard Nixon Presidential Library & Museum
Presidential museum, birthplace and helicopter
Arboretum and Botanical Garden at Cal State Fullerton
Botanical paths with native and desert plants
Summit House Restaurant
Hilltop prime rib restaurant with city views
Ayres Suites Yorba Linda
Quiet suburban hotel with surface parking
Hidden Valley Nature Trailhead
Short loop among boulders and Joshua trees
Keys View
High panorama across the Coachella Valley
JT Country Kitchen
Wagon Wheel Restaurant
Classic Route 66-style American diner
Best Western Colorado River Inn
Reliable roadside hotel with pool and parking
Oatman AZ
Mining town, Route 66 buildings and wild burros
Arizona Route 66 Museum
Migration and highway history in a power station
Mr D'z Route 66 Diner & Gift Shop
Colorful Route 66 diner with classic fare
Seligman Commercial Historic District
Preserved Route 66 storefronts and neon
Josephine's Restaurant
Seasonal bistro in a historic cottage
Little America Hotel
Woodland hotel with spacious surface parking
Walnut Canyon National Monument
Cliff dwellings and canyon-rim trails
Meteor Crater Natural Landmark
Preserved impact crater with guided rim access
Turquoise Room
Regional Southwestern dining at La Posada
Standin' on the Corner Park
Route 66 landmark and public art corner
Butterfield Stage Co. Steak House
Local steakhouse near historic Route 66
La Quinta Inn & Suites by Wyndham Holbrook Petrified Forest
Modern roadside hotel with open parking
George Galanis Multi Cultural Center
Native arts and regional railway history
El Malpais National Monument Visitor Center
Lava-field geology and hiking information
El Cafecito
Family-run New Mexican café
El Pinto Restaurant & Cantina
Landmark New Mexican restaurant and patios
Hotel Albuquerque at Old Town
Southwestern hotel beside historic Old Town
Indian Pueblo Cultural Center
Pueblo history, art and living cultures
Range Cafe Downtown
New Mexican comfort food and baked goods
Pecos National Historical Park
Pueblo ruins and Santa Fe Trail history
Blue Hole
Deep artesian spring with vivid blue water
Joseph's Bar & Grill
Historic Route 66 New Mexican restaurant
La Quinta Inn & Suites by Wyndham Santa Rosa
Interstate hotel with practical parking
Tucumcari Historical Museum
Local history inside a 1903 schoolhouse
Cadillac Ranch
Iconic roadside art installation in a field
Coyote Bluff Cafe
Tiny local institution for burgers and green chile
American Quarter Horse Hall of Fame & Museum
Western horse history, art and bloodlines
White Dog Hill Restaurant
Hilltop regional restaurant in a historic building
La Quinta Inn & Suites by Wyndham Clinton Historic Route 66
Modern Route 66 hotel with open parking
Oklahoma City National Memorial & Museum
Powerful memorial and documented civic history
Cattlemen's Steakhouse
Historic Stockyards City steakhouse
Philbrook Museum of Art
Art museum and gardens in an Italianate villa
Living Kitchen Farm and Dairy
Farm-based Oklahoma tasting experience
Hampton Inn & Suites Stroud
Route 66 hotel with easy exterior parking
Route 66 State Park
Highway museum and Meramec River trails
The Crossing
Seasonal St. Louis-area lunch restaurant
Cahokia Mounds UNESCO World Heritage Site
Pre-Columbian city and monumental earthworks
Before you go
Local tips
- 1Reserve Arches timed entry as soon as the May 2027 booking window opens.
- 2Book Georgetown Loop Railroad, Sandia Peak Tramway and Neon Museum timed tickets before departure.
- 3Start Utah and California desert hikes before 09:00; late-May temperatures can rise quickly.
- 4Fill the SUV before crossing Mojave National Preserve and again before long New Mexico plains sections.
- 5Use hotel or surface parking in Denver, Las Vegas and historic districts rather than assuming garage clearance.
- 6Check Memorial Day weekend crowd notices for Joshua Tree, Flagstaff and Petrified Forest.
Good to know
- 1Colorado high-country roads and trails may retain snow; UT-153 to Eagle Point can remain seasonally inaccessible.
- 2CA-241 in Orange County uses electronic tolling; register the SUV plate or arrange payment promptly.
- 3Nevada and California desert heat can exceed seasonal averages, and parked-vehicle temperatures endanger camera batteries.
- 4Oatman Highway has steep, narrow curves over Sitgreaves Pass; descend in a lower gear and watch for burros.
- 5Thunderstorms can produce hail and sudden crosswinds across Nebraska, eastern Colorado, Texas and Oklahoma.
- 6Holiday traffic may delay I-15, Joshua Tree entrances and Flagstaff approaches over Memorial Day weekend.